FC Halifax Town play their last league match of the season at Stalybridge on Saturday (April 27, 3pm kick-off).
The Shaymen can still finish fourth in the table if they win and Altrincham fail to beat Droylsden.
But Guiseley look likely to be Town’s play-off semi-final opponents, and manager Neil Aspin may take the opportunity to rest his key players ahead of the first-leg on Tuesday.
Scott McManus and James Bolton both picked up knocks in the 1-1 draw with Chester on Thursday, so are unlikely to feature, as is Adriano Moke, who could miss the play-off campaign completely with a thigh injury.
Phil Senior is expected to replace Matt Glennon in goal, while Jason St Juste and Adam Jackson could also feature from the start after being named as substitutes on Thursday.
Stalybridge are currently 16th in the table, but could climb up to 13th if they win, which would extend their current unbeaten run to nine games, which includes draws against Harrogate and Guiseley.
Only three teams have scored fewer goals in the Conference North this season than Stalybridge, who drew 0-0 in the reverse fixture at Rochdale’s Spotland ground earlier in the year.